产品货号：
Z35496
中文名称：
OPA1抗体
英文名称：
Anti-OPA1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-OPA1 Antibody |
| 指标别名 | KIAA0567;largeG;MGM1;NTG;OPA1;Optic atrophy protein 1 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | OPA1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human OPA1 Dynamin-related GTPase required for mitochondrial fusion and regulation of apoptosis.May form a diffusion barrier for proteins stored in mitochondrial cristae.Proteolytic processing in response to intrinsic apoptotic signals may lead to disassembly of OPA1 oligomers and release of the caspase activator cytochrome C (CYCS) into the mitochondrial intermembrane space. |
| 实际分子量 | 80～100KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Dynamin-like 120kDa protein,mitochondrial is a protein that in humans is encoded by the OPA1 gene.It is mapped to 3q29.This protein regulates mitochondrial fusion and cristae structure in the inner mitochondrial membrane (IMM) and contributes to ATP synthesis and apoptosis.This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases.It is a component of the mitochondrial network.Mutations in this gene have been associated with optic atrophy type 1,which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity,leading in many cases to legal blindness.Multiple transcript variants encoding different isoforms have been found for this gene. |
| Uniprot ID | O60313 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100ICC/IF 1:50～1:200 FC 1:50 |
相关搜索：OPA1抗体，OPA1单抗，Anti-OPA1 Antibody